Quadruple Screening in the Age of Cell-Free DNA: What are We Losing?
نویسندگان
چکیده
Cell-free DNA has emerged as the most reliable, non-invasive prenatal screening tool for fetal aneuploidies. It come to replace previously widely used quadruple screen offered in second trimester of pregnancy. This change comes with improved detection aneuploidy but also presents potential gaps diagnosis including open defects and emerging data on prediction adverse pregnancy outcomes. review article provides a historical summary marker evaluates intersection this cell-free DNA. Furthermore, it discusses points consider providers trend toward testing alone reviews options remedy any disparities.
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ژورنال
عنوان ژورنال: OBM genetics
سال: 2021
ISSN: ['2577-5790']
DOI: https://doi.org/10.21926/obm.genet.2103138